Some eye care practitioners have reported that comfort-related issues in Air Optix Night & Day contact lenses are caused by users inserting them inside-out.
The Air Optix Night & Day Aqua contact lenses have an inversion indicator on the edge of the contact lens that shows "OK" when the lens is in its proper form and is ready to be placed into your eye. If the inversion indicator reads "ʞo", it should be restored to its proper shape before wearing.
If inserting them correctly isn't an issue, but you are still experiencing discomfort, it could be that you're prone to heavy deposits. As a first measure, using Clear Care Cleaning & Disinfection Solution may help reduce the symptoms. If discomfort persists, contact your eye care professional.